I get up… bright and early with our son. He’s two, and has yet to learn the art of the lie in. Depending on whether I am doing the nursery drop-off, and on the temperament of the Victoria Line, I usually arrive at Birkbeck between 8.00 and 9.00am. The first thing I do is switch on the lights in the laboratory, and think about what experiments the day will hold.
My research investigates… walking proteins. These molecules have legs one hundred million time smaller than ours, and walk along filaments inside the individual cells that make up our body. It has emerged that they are important for human health: their dysfunction is associated with a number of currently untreatable diseases, such as neurodegeneration. The ability of these proteins to walk correctly is vital, because they transport key materials in the cell to the right place at the right time. We want to know how this works at the molecular level.
I teach… mainly to students doing research projects in the laboratory. This is exciting, because it is teaching while attempting to discover something new at the same time. I also lecture to MRes and PhD students on the main techniques we use in our research, particularly microscopes that enable one to view individual molecules.
My typical day… has no predictable pattern, and this variety is one of my favourite parts of my job. Some days will be spent mostly in the laboratory, for example purifying the proteins that we study. This work has a pace not dissimilar to cooking, with multiple stages and incubations – although alas less delicious smells! Others will be on the microscopes, or analysing data. As the lab grows, I spend less time doing experiments myself, and more time talking to others about their data, and preparing grants, research papers, and seminars. The data we obtain from our research is very visual: thinking about ways to extract and present the important insights is a nice balance to these literary tasks.
I became a scientist… in a somewhat roundabout way. As a child, I wanted to be an artist. This interest in the visual remains a strong part of who I am. Later, I became curious about biology, and enjoyed the hard answers that maths and chemistry could provide. I did an undergraduate course in Biochemistry, really engaging with it as it transitioned from memorising facts to solving problems. In hindsight, it makes sense that I gravitated to what I work on now, as it combines all of these elements, but a number of fortuitous events made it happen. Chief among them were training with terrific mentors during my PhD and postdoctoral studies: Stan Burgess, Peter Knight and Samara Reck-Peterson.
My greatest professional achievement to date has been… obtaining the Sir Henry Dale Fellowship from the Wellcome Trust and Royal Society, which enabled me to start the laboratory at Birkbeck. The scale and flexibility of its support are a great help towards realising research ideas.
After work… it is nice to do something completely different. We like finding new places to eat and drink around where we live in east London, cooking, music, art and design, and relaxing.
My favourite part of my job is… the first glimpse of a new discovery, to be shared with lab members, students, and other scientists.. .